Tools for COVID-19 Research (Proteomics)

Since the end of 2020, different SARS-CoV-2 variants have appeared worldwide − alpha (B.1.1.7), beta (B.1.351), gamma (P.1/B.1.1.128), delta (B1.617.2), and omicron (B.1.1.529) – which show differences in transmissibility as well as disease severity compared with the original virus. These variants are mainly defined by mutations in the spike protein, which are critical viral entry into human host cells. Genomax supplies a selection of SARS-CoV-2 ELISA kits and reagents that serve to help researchers quantify IgG antibodies against the SARS-CoV-2 Omicron or Delta spike variant proteins in human serum.

If you require more information on COVID-19 research assays, antibodies, and recombinant proteins, please contact us with any questions at info@genomax.com.sg.

Interested in COVID-19 ELISAs?

Genomax also supplies high Sensitivity Assays for IgG, IgM, IgA to the N/S-Proteins. Detect IgG, IgM, and IgA antibodies to SARS-CoV-2 N and S1 RBD proteins in serum, plasma, dried blood, and saliva samples.

Antibodies for research

Viral entry and the resulting inflammation are key mechanisms under investigation by SARS-CoV-2 researchers. BioLegend provides SARS-CoV-2 recombinant proteins and antibodies to investigate the interactions between S1 spike protein and human ACE2 for viral entry.

Browse antibodies from BioLegend:

Fighting the COVID-19 pandemic requires an arsenal of research tools and reagents. RayBiotech provides the most complete and comprehensive range of products and services to support your efforts in SARS-CoV-2 research and development of therapies and vaccines.

Antibody screening has important public health uses in determining immunity to and prevalence of COVID-19, as well as identifying who has been infected and evaluating potential blood based therapeutics. Detect IgG, IgM, and IgA antibodies to SARS-CoV-2 N and S proteins using the indirect ELISA kits from RayBiotech. Binding assays are available to determine if the antibodies present can inhibit cell binding, are neutralizing, or suitable for vaccine development.

Read more: COVID-19 Tools for Antibody Screening including COVID-19 ELISA kits, COVID-19 Spike Protein Array, COVID-19 Binding Assay, and COVID-19 Pseudovirus Service.

Browse antibodies from RayBiotech:

Featured ELISA Kits and Sets for IgG, IgM, IgA to the N/S-Proteins

Browse ELISA Kits and Sets from BioLegend:

Browse featured ELISA Kits from Revvity (Cisbio):

Browse featured SARS-CoV-2 Omicron and Delta Variant ELISA Kits Kits from RayBiotech:

– The B.1.1.529 variant was classified as a variant of concern in November 2021. The Omicron spike protein contains some 30 amino acid substitutions, 15 of which are within the receptor binding domain (RBD). These include G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, and Y505H.

– The B.1.617.2 variant was first identified in as a variant of concern in December 2020. This variant is defined by 10 mutations: 19R, (G142D), 156del, 157del, R158G, L452R, T478K, D614G, P681R, D950N in the spike protein.

Featured ELISA Kits and Sets for IgG, IgM, IgA to the N/S-Proteins

Browse ELISA Kits and Sets from BioLegend:

Browse featured ELISA Kits from Revvity (Cisbio):

Browse featured SARS-CoV-2 Omicron and Delta Variant ELISA Kits Kits from RayBiotech:

– The B.1.1.529 variant was classified as a variant of concern in November 2021. The Omicron spike protein contains some 30 amino acid substitutions, 15 of which are within the receptor binding domain (RBD). These include G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, and Y505H.

– The B.1.617.2 variant was first identified in as a variant of concern in December 2020. This variant is defined by 10 mutations: 19R, (G142D), 156del, 157del, R158G, L452R, T478K, D614G, P681R, D950N in the spike protein.

Featured LEGENDplex™ Panels from BioLegend

BioLegend’s LEGENDplex™ bead-based immunoassays quantify multiple soluble analytes simultaneously in biological samples using a flow cytometer.

Browse these featured LEGENDplex™ panels:

Uncover Antigen-specific T Cells for SARS-CoV-2 research

Looking for the right alleles for tetramer staining? Use the Flex-T™ MHC tetramers from BioLegend to discover more T cell specificities. These reagents allow easy and flexible sample screening by allowing you to load your peptide of interest, customize fluorophore combinations, and choose from an expanding range of MHC alleles.

Learn more about Flex-T MHC Tetramer staining.

Browse the Flex-T™ MHC reagents:

Featured COVID-19 Protein Arrays for your research

RayBiotech’s Peptide and protein arrays can give you a detailed map of interactions by high-throughput screening of SARS-CoV-2 immunoreactivity.

Browse these featured COVID-19 Protein Arrays:

  • – Contains overlapping peptides representing the full-length SARS-CoV-2 Spike protein and is ideal for measuring IgG, IgM, or IgA antibody responses to immunization or COVID-19 infection and identifying immunodominant epitopes within the SARS-CoV-2 spike protein.

    – A semi-quantitative array displaying 22 important coronavirus spike (S) and nucleocapsid (N) proteins derived from SARS-CoV-2 (Covid-19) alpha to lambda variants, SARS-CoV, MERS-CoV, and HcoV-HKU1. It is suitable for antibody detection in serum, plasma, and other liquid sample types.

Featured Recombinant Proteins

Browse recombinant proteins from RayBiotech:

  • Recombinant SARS-CoV-2 Proteins – COVID-19 Proteins
  • SARS, MERS, and HKU1 Coronavirus Proteins
  • Thrombosis Proteins – Thrombosis, or blood clotting, obstructs blood flow through the circulatory system and can be caused by numerous factors. Inflammation associated with SARS-CoV-2 or COVID-19 infection can lead to a type of thrombosis called “disseminated intravascular coagulopathy” (DIC) that affects the lung, heart, or kidneys. DIC in COVID-19 patients initially presents with abnormalities in prothrombin time, partial thromboplastin time, and platelet counts. RayBiotech’s functional thrombosis proteins are ideal for developing coagulation assays to assist with DIC monitoring.

At each and every step of your workflow, we want to be able to disrupt and dismantle the SARS-CoV-2 virus. This means understanding the functions of the proteins encoded by the virus genome, and the host entry points and pathways it utilizes. It means discerning effective immune responses in COVID-19 patients and disease models. And it means discovering new biomarkers and pathways for therapeutic treatments, vaccine candidates, and viral detection kits. BioLegend supplies a diverse portfolio of products (antibodies, recombinant proteins, cytokine detection kits, and proteogenomics profiling options) by workflow stages, making it easier to pick your reagents and start your experiments.

Discover more about BioLegend’s tools for SARS-CoV-2 research.

Browse recombinant proteins from BioLegend:

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