Targeted sequencing provides a time and cost-effective workflow by investigating specific regions in the genome. Hybrid capture-based target enrichment employs probes to capture target sequences in a NGS library. Hybrid capture sequencing is sensitive and suited for detecting single nucleotide variants, translocations, structural variants, insertions and deletions, and copy number variations. Agilent provides a full suite of hybridization capture-based target enrichment NGS products, including library preparation and target enrichment kits, exomes, catalog and custom probes, software solutions, sample quality control and automation platforms. Whether your research needs a catalog NGS panel or a custom design to include your genes of interest, Agilent has the solutions for you. Agilent offers other amplicon-based target enrichment technology options, also, for finding specific regions-of-interest time. 

miRNAs (microRNAs) are small single-stranded non-coding RNAs (19-30 nucleotides long) that play a widespread role in post-transcriptional gene silencing. Agilent miRNA microarrays provide unmatched performance in high throughput miRNA profiling.

Recently tested in the miRQC study¹, Agilent SurePrint miRNA Microarrays exhibited performance superior to qPCR, sequencing, and other microarray platforms for consistent miRNA detection by showing the highest titration response, reproducibility, and precision in accuracy.

Now updated to release 21, Agilent miRNA microarrays are available pre-designed for human, mouse, and rat species. Or, design your custom microarray to have any or all available miRNA target probes. The latest miRBase database release 21 has a total of 28,645 entries in 223 species, an increase of 4,196 new hairpin sequences from release 20.

Better content

• Latest miRBase 21 content
• Pre-designed microarrays available for human, mouse, and rat species

Better flexibility

• Customizable microarray design to target any set of miRNA probes in multiple array formats and spot diameters
• Create multi-species miRNA microarrays – all 223 species available from miRBase 21

Better performance

• Highest titration response, reproducibility, and precision in accuracy
• High sensitivity with a dynamic range up to 6 orders of magnitude using only 100 ng of total RNA

Choose from a wide selection of catalog gene expression microarrays for the sensitive detection of mRNA, lincRNA, miRNA, and exon microarrays for exon-level profiling. Complete the solution with high-quality microarray processing tools that deliver accuracy and precision so you produce outstanding results every time.

• In situ deposition of individual nucleotides builds 60 to 200-mer oligonucleotides
• Advanced inkjet technology delivers densities of 1 million features per microarray
• Up to 8 arrays on a single slide for genome-wide or focused studies

The SureSelect Human All Exon V6 is a high performing design that targets updated content, including challenging regions, from the databases relevant to both the clinical and translational researchers. Optimized bait selection and boosting enables highly uniform coverage of the exome and each individual targeted exon. This improvement helps address the current observation of the inverse correlation between depth of coverage and breadth of coverage providing balanced coverage, maximizing variant information output for per exome sequenced.

The Agilent 4200 TapeStation system offers automated sample processing for quick and reliable sample quality control within any Next Generation Sequencing (NGS), microarray (aCGH) or quantitative PCR (qPCR) workflow.

• Automated - Unattended walk away operation with fully automated sample processing for up to 96 samples.
• Scalable - Individual channels facilitate variable throughput from 1 - 96 samples at a constant cost.
• Flexible - Ready-to-use ScreenTape technology enable easy switching between DNA and RNA assays. Sample can be provided in either two 8-tube strips or 96 well plates.
• Fast - Simplify your workflow without any system set up procedures and obtain reliable results in as little as 1-2 minutes per sample, even for 96 samples. 
• Low-Throughput Option available - 4150 Tapestation system available for laboratories that process 1-16 samples or require smaller instrument footprint.

Nugen's Ovation RNA-Seq V2

GeneSpring provides powerful, accessible statistical tools for intuitive data analysis and visualization. Designed specifically for the needs of biologists, GeneSpring offers an interactive environment that promotes investigation and enables understanding of Transcriptomics, Genomics, Metabolomics and Proteomics data within a biological context.  NGS data can be aligned and analyzed in Strand NGS (Agilent’s business partner – free trial), and the imported reads, region and entities can be visualized in GeneSpring the Genome Browser, and further correlated with other data types. GeneSpring allows you to quickly and reliably identify targets of interest that are both statistically and biologically meaningful.

• Statistical Analysis
• Clustering and PCA
• Multi-omic Analysis for Integrated Biology
• Pathway Analysis and Visualizations

Comprehensive Target Enrichment Panel for Genome-Wide Copy Number, LOH and Targeted Mutations - in ONE assay.